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Once in the stroma, tumor cells can then penetrate the walls of blood vessels or the lymphatic system and enter into the circulation.Local tissue invasion and the formation of metastatic lesions are characteristic properties of many malignant tumors.The formation of metastases is a complex process involving the passage of tumor cells from the site of the primary bulk tumor through successive connective tissue barriers, ultimately resulting in the growth of secondary tumor cell colonies in distinct target organ locations.Specifically, the role of basement membrane at a barrier to metastatic tumor cells is examined.Home About Us Blog Genealogy Recipes Gardening Manners and Etiquette Real Estate Destinations History Art Hunting and Fishing Photojournalism Southern Furniture Maker Inspiration Write Life Opinion Contact- ) was born January 22, 1570/71 in Connington, Huntingdonshire, England.

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